Silinganise amazinga omchamo we-3-phenoxybenzoic acid (3-PBA), i-pyrethroid metabolite, kubantu base-Korea basemakhaya nabasemadolobheni asebekhulile abangu-1239. Siphinde sahlola ukuchayeka kwe-pyrethroid sisebenzisa umthombo wedatha wohlu lwemibuzo;
Isibulala-zinambuzane sasekhayaizifutho ziwumthombo omkhulu wokuchayeka ezingeni lomphakathi kuma-pyrethroids kubantu abadala asebekhulile eSouth Korea, okuxwayisa ngesidingo sokulawulwa okukhulu kwezici zemvelo lapho ama-pyrethroids avame ukuchayeka khona, okuhlanganisa izifutho zezibulala-zinambuzane.
Ngenxa yalezi zizathu, ukufunda imiphumela ye-pyrethroids kubantu asebekhulile kungase kubaluleke eKorea nakwamanye amazwe anabantu asebekhulile abakhula ngokushesha. Kodwa-ke, kunenani elilinganiselwe lezifundo eziqhathanisa ukuchayeka kwe-pyrethroid noma amazinga we-3-PBA kubantu abadala asebekhulile ezindaweni zasemakhaya noma zasemadolobheni, futhi izifundo ezimbalwa zibika imizila engase ibe khona yokuchayeka kanye nemithombo engaba khona yokuchayeka.
Ngakho-ke, silinganise amaleveli angu-3-PBA kumasampula omchamo wabantu abadala e-Korea futhi saqhathanisa ukugxiliswa kwe-3-PBA emchameni wabantu asebekhulile basemakhaya nabasemadolobheni. Ngaphezu kwalokho, sihlole ingxenye eyeqa imikhawulo yamanje ukuze sinqume ukuchayeka kwe-pyrethroid phakathi kwabadala asebekhulile e-Korea. Siphinde sahlola imithombo engaba khona yokuchayeka kwe-pyrethroid sisebenzisa uhlu lwemibuzo futhi sayihlobanisa namazinga omchamo angu-3-PBA.
Kulolu cwaningo, silinganise amazinga omchamo angu-3-PBA kubantu abadala base-Korea abahlala ezindaweni zasemakhaya nasemadolobheni futhi sahlola ubudlelwano phakathi kwemithombo engaba khona yokuchayeka kwe-pyrethroid kanye namazinga angu-3-PBA womchamo. Siphinde sanquma ingxenye yokweqisa kwemikhawulo ekhona futhi sahlola umehluko phakathi komuntu ngamunye kumaleveli angu-3-PBA.
Ocwaningweni olushicilelwe ngaphambilini, sithole ukuhlobana okubalulekile phakathi kwamazinga womchamo we-3-PBA kanye nokwehla kokusebenza kwamaphaphu kubantu abadala basemadolobheni aseNingizimu Korea [3]. Ngenxa yokuthi sithole ukuthi abantu abadala basezindaweni zasemadolobheni e-Korea babechayeke emazingeni aphezulu e-pyrethroids ocwaningweni lwethu lwangaphambilini [3], saqhubeka siqhathanisa amazinga omchamo angu-3-PBA wabantu abadala basemakhaya nabasemadolobheni ukuze sihlole izinga lamanani okweqile epyrethroid. Lolu cwaningo lwabe seluhlola imithombo engaba khona yokuchayeka kwe-pyrethroids.
Isifundo sethu sinamandla amaningana. Sisebenzise izilinganiso eziphindaphindiwe ze-urinary 3-PBA ukuze sibonise ukuchayeka ku-pyrethroid. Lo mklamo wephaneli ye-longitudinal ungase ubonise izinguquko zesikhashana ekuvezweni kwe-pyrethroid, ezingashintsha kalula ngokuhamba kwesikhathi. Ukwengeza, ngalo mklamo wocwaningo, singahlola isihloko ngasinye njengokulawula kwakhe futhi sihlole imiphumela yesikhathi esifushane yokuchayeka kwe-pyrethroid sisebenzisa i-3-PBA njenge-covariate yenkambo yesikhathi phakathi kwabantu ngabanye. Ngaphezu kwalokho, sibe ngabokuqala ukuhlonza imithombo yemvelo (okungeyona eyemisebenzi) yokuchayeka kwe-pyrethroid kubantu abadala asebekhulile e-Korea. Nokho, isifundo sethu sinokulinganiselwa. Kulolu cwaningo, siqoqe ulwazi ngokusetshenziswa kwezifutho ezibulala izinambuzane sisebenzisa uhlu lwemibuzo, ngakho-ke isikhathi esiphakathi kokusetshenziswa kwezifutho ezibulala izinambuzane nokuqoqwa komchamo asikwazanga ukunqunywa. Nakuba amaphethini okuziphatha okusetshenziswa kwesifutho esibulala izinambuzane engaguquki kalula, ngenxa yemetabolism esheshayo ye-pyrethroids emzimbeni womuntu, isikhawu sesikhathi phakathi kokusetshenziswa kwesifutho esibulala izinambuzane nokuqoqwa komchamo kungaba nomthelela omkhulu ekugxilweni komchamo okungu-3-PBA. Ukwengeza, ababambiqhaza bethu bebengameleleki njengoba besigxile endaweni eyodwa kuphela yasemaphandleni neyodwa yasemadolobheni, nakuba amazinga ethu angu-3-PBA ayeqhathaniswa nalawo akalwa kubantu abadala, okuhlanganisa nabantu abadala, ku-KoNEHS. Ngakho-ke, eminye imithombo yezemvelo ehlotshaniswa nokuchayeka kwe-pyrethroid kufanele iqhutshekwe ifundwe kubantu abamele abantu abadala.
Ngakho-ke, abantu abadala asebekhulile eKorea bachayeka ekugxilweni okuphezulu kwama-pyrethroids, nokusetshenziswa kwezifutho zokubulala izinambuzane kuwumthombo oyinhloko wokuchayeka kwemvelo. Ngakho-ke, ucwaningo olwengeziwe luyadingeka ngemithombo yokuchayeka kwe-pyrethroid phakathi kwabantu abadala asebekhulile eKorea, futhi ukulawulwa okuqinile ezicini zemvelo ezivame ukudalulwa, kuhlanganise nokusetshenziswa kwezifutho zokubulala izinambuzane, kuyadingeka ukuze kuvikelwe abantu abangenwe yi-pyrethroids, kuhlanganise nokuchayeka kumakhemikhali emvelo. abantu abadala.
Isikhathi sokuthumela: Sep-27-2024