Abacwaningi abavela eMnyangweni we-Biochemistry e-Indian Institute of Sciences (IISc) bathole indlela ekade ifunwa yokulawula ukukhula kwezitshalo zasendulo ezifana ne-bryophytes (iqembu elihlanganisa ama-mosses nama-liverwort) agcinwe ezitshalweni eziqhakaza kamuva.
Lolu cwaningo, olushicilelwe kumagazini i-Nature Chemical Biology, lugxile ekulawulweni okungekona okwe-canonical kwamaprotheni e-DELLA, umlawuli wokukhula oyinhloko ovimbela ukuhlukaniswa kwamaseli kuma-embryophyte (izitshalo zomhlaba).
Ngokuthakazelisayo, ama-bryophyte, izitshalo zokuqala ukuvela emhlabeni eminyakeni engaba yizigidi ezingu-500 edlule, awanawo ama-receptor e-GID1 naphezu kokukhiqiza i-phytohormone GA. Lokhu kuphakamisa umbuzo wokuthi ukukhula nokuthuthukiswa kwalezi zitshalo zokuqala zomhlaba kwakulawulwa kanjani.
Besebenzisa i-liverwort Marchantia polymorpha njengohlelo lwemodeli, abacwaningi bathole ukuthi lezi zitshalo zakudala zisebenzisa i-enzyme ekhethekile, i-MpVIH, ekhiqiza i-cellular messenger inositol pyrophosphate (InsP₈), evumela ukuthi ziphule i-DELLA ngaphandle kwesidingo se-gibberellic acid.
Abacwaningi bathole ukuthi i-DELLA ingenye yezinhloso zamaseli ze-VIH kinase. Ngaphezu kwalokho, baqaphele ukuthi izitshalo ezingenayo i-MpVIH zilingisa izinhlobo zezitshalo ze-M. polymorpha eziveza i-DELLA ngokweqile.
“Kuleli qophelo, besijabule kakhulu ukuqonda ukuthi ukuzinza noma umsebenzi we-DELLA uyakhuphuka yini ezitshalweni ezingenayo i-MpVIH,” kusho uPriyanshi Rana, umbhali wokuqala kanye nomfundi ophothule eqenjini locwaningo likaLahey. Ngokuvumelana nombono wabo, abacwaningi bathole ukuthi ukuvimbela i-DELLA kusindise kakhulu ukukhula okunephutha kanye nentuthuko yezitshalo eziguquliwe ze-MpVIH. Le miphumela iphakamisa ukuthi i-VIH kinase ilawula kabi i-DELLA, ngaleyo ndlela ikhuthaze ukukhula kanye nentuthuko yezitshalo.
Ucwaningo ngamaprotheni e-DELLA luqala emuva ku-Green Revolution, lapho ososayensi bengazi besebenzisa amandla abo okuthuthukisa izinhlobo ze-semi-dwarf ezikhiqiza kakhulu. Nakuba imininingwane yokuthi zazisebenza kanjani yayingacacile ngaleso sikhathi, ubuchwepheshe besimanje buvumela ososayensi ukuthi balawule imisebenzi yala maprotheni ngobunjiniyela bezakhi zofuzo, bandise ngempumelelo isivuno sezitshalo.
Ukufunda izitshalo zakuqala zomhlaba nakho kunikeza ukuqonda ngokuvela kwazo eminyakeni eyizigidi ezingama-500 edlule. Isibonelo, yize izitshalo zezimbali zanamuhla ziphazamisa amaprotheni e-DELLA ngokusebenzisa indlela encike ku-gibberellic acid, izindawo zokubopha ze-InsP₈ ziyalondolozwa. Lokhu okutholakele kunikeza ukuqonda ngokuvela kwezindlela zokubonisana kwamaseli ngokuhamba kwesikhathi.
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Isikhathi sokuthunyelwe: Septhemba 15-2025