I-Aspirin enamandla kakhulu yokulwa nokuvuvukala kanye ne-analgesic

Incazelo Yomkhiqizo

I-aspiriniingamuncwa ngokushesha engxenyeni engaphambili yesisu namathumbu amancane ngemva kokuthatha i-aspirin esiswini esisodwa. Izinkomo nezimvu zimunca kancane, cishe ama-70% ezinkomo ayamuncwa, isikhathi esiphezulu sokuhlushwa kwegazi singamahora ama-2-4, kanti ingxenye yokuphila ingamahora ama-3.7. Izinga lakhe lokubopha amaprotheni e-plasma lalingu-70% ~ 90% emzimbeni wonke. Ingangena ubisi, kodwa ukuhlushwa kuphansi kakhulu, ingadlula futhi emgoqweni we-placental. I-hydrolyzed kancane ibe yi-salicylic acid ne-acetic acid esiswini, i-plasma, amaseli egazi abomvu nezicubu. Ikakhulukazi ekugayweni kwesibindi, ukwakheka kwe-glycine kanye ne-glucuronide junction. Ngenxa yokuntuleka kwe-gluconate transferase, ikati liphila isikhathi eside futhi lizwela kulo mkhiqizo.

Isicelo

Ukwelapha umkhuhlane, isifo samathambo, imizwa, imisipha, ubuhlungu bamalunga, ukuvuvukala kwezicubu ezithambile kanye ne-gout ezilwaneni.