Isibulala-zinambuzane sebhayoloji iThiostrepton CAS No 1393-48-2 I-Thiostrepton Powder

Isingeniso

I-Thiostreptoniyi-antibiotic enamandla etholakala emikhiqizweni yokubilisa yezinhlobo ezithile zebhaktheriya i-Actinomycete. Ingaphansi kwesigaba se-thiopeptide sama-antibiotic futhi ithole ukuqashelwa ngokusebenza kwayo okuphawulekayo ngokumelene namagciwane ahlukahlukene e-Gram-positive, okuhlanganisa i-MRSA (i-methicillin-resistant Staphylococcus aureus).I-Thiostreptoniye yafundwa kabanzi futhi ibonise ithemba ezindleleni ezahlukene zezokwelapha, zezilwane, kanye nezolimo. Ngezici zayo eziyingqayizivele kanye nezakhiwo zayo ezivelele zokulwa namagciwane, iThiostrepton iyaqhubeka nokuguqula insimu yokwelapha ngama-antibiotic.

Ukusetshenziswa

Ukusetshenziswa okuyinhloko kweThiostrepton kusekwelapheni nasekuvimbeleni ukutheleleka ngamagciwane. Ivimbela ukwakheka kwamaprotheni kumagciwane, ngaleyo ndlela ivimbele ukukhula nokwanda kwawo. Lokhu kuyenza ithuluzi elibalulekile ekulweni nezifo ezahlukahlukene ezibangelwa amagciwane ane-Gram-positive, kusukela ekuthelelekeni kwesikhumba kuya ekuthelelekeni kokuphefumula. Ngaphezu kwalokho, iThiostrepton iphinde yabonakala isebenza kahle ekuthelelekeni okuthile kwesikhunta. Umsebenzi wayo obanzi uyivumela ukuthi ihlasele izinhlobo eziningi zamagciwane, okwenza kube yi-antibiotic ehlukahlukene.

Isicelo

1. Ukunakekelwa Kwempilo Kwabantu: I-Thiostrepton ibonise amandla amakhulu ekusetshenzisweni kwezempilo kwabantu. Ivame ukusetshenziswa ekwelapheni izifo zesikhumba ezifana ne-impetigo, i-dermatitis, kanye ne-cellulitis ebangelwa yi-Staphylococcus aureus kanye ne-Streptococcus pyogenes. Ngaphezu kwalokho, i-Thiostrepton ibonise imiphumela ethembisayo ekwelapheni izifo zokuphefumula, okuhlanganisa i-pneumonia kanye ne-bronchitis. Umsebenzi wayo wokulwa ne-MRSA, uhlobo oludumile olumelana nama-antibiotic, uyenze yaba usizo kakhulu ezibhedlela.

2. Ukwelapha Ngezilwane: I-Thiostrepton isetshenziswe kakhulu kwezokwelapha ngezilwane. Ibhekana nokutheleleka okuhlukahlukene kwamagciwane okuthinta imfuyo, izinkukhu, kanye nezilwane ezihambisana nayo. Ukusebenza kwayo kahle emagciwaneni avamile njenge-Staphylococcus, i-Streptococcus, kanye nezinhlobo ze-Clostridium kube negalelo elikhulu ekuthuthukiseni impilo yezilwane kanye nenhlalakahle yazo. Ngaphezu kwalokho, iphrofayili yokuphepha enhle kakhulu ye-Thiostrepton iyenza ibe ukukhetha okuhle kokwelapha izifo ezilwaneni, inciphise imiphumela emibi engaba khona.

3. Ezolimo: I-Thiostrepton inamandla amakhulu ekusetshenzisweni kwezolimo. Ingalwa namagciwane ezitshalweni njenge-Actinomyces kanye ne-Streptomyces, inciphise ukwanda kwezifo zezitshalo futhi ithuthukise isivuno. I-Thiostrepton ingasetshenziswa njengesifutho samaqabunga noma ekwelapheni imbewu ukuze ivikeleke ekuthelelekeni ngesikhunta kanye namagciwane ezitshalweni ezahlukene. Ngokulawula izifo zezitshalo ngempumelelo, i-Thiostrepton inegalelo kwezolimo ezisimeme kanye nokuvikeleka kokudla.

Izici

1. Amandla: I-Thiostrepton yaziwa ngamandla ayo akhethekile okulwa namagciwane amaningi ayingozi kanye nesikhunta. Isebenza ngokuvimbela ngokukhetha ukwakheka kwamaprotheni ebhaktheriya, iqinisekisa isenzo esiqondiwe ngokumelene namagciwane abangela izifo ngenkathi ilondoloza amagciwane anenzuzo.

2. I-Broad Spectrum: I-spectrum yomsebenzi we-Thiostrepton ihlanganisa amabhaktheriya amaningi ane-Gram-positive kanye nezinhlobo ezithile ze-anaerobic. Lokhu kuguquguquka kuvumela ukusetshenziswa okubanzi ezindaweni ezahlukene zezokwelapha, zezilwane, kanye nezolimo.

3. Ukuphepha: I-Thiostrepton inephrofayili yokuphepha enhle kakhulu, okwenza ifaneleke ukusetshenziswa ezinhlotsheni ezahlukahlukene. Ubuthi bayo obuphansi kanye nemiphumela emibi engabaluleki kahle ivumela ukusetshenziswa kwayo ezindaweni ezibucayi, njengeyunithi ye-ICU kanye namapulazi ezilwane.

4. Ukuvimbela Ukumelana: Ngokungafani namanye ama-antibiotic, i-Thiostrepton ibonise ukuthambekela okuphansi kokuthuthukiswa kokumelana namagciwane ngenxa yendlela yayo yokusebenza ehlukile. Lokhu kuyenza ithuluzi elibalulekile ekulweni nenkinga ekhulayo yokumelana namagciwane.

5. Izinhlobo Zokwenziwa: I-Thiostrepton itholakala ngezindlela ezahlukene, okuhlanganisa okhilimu, amafutha okugcoba, imijovo, kanye nezifutho. Lokhu kwenza kube lula ukunikezwa ezindaweni ezahlukene zezempilo nezolimo, okwenza kube lula abahlinzeki bezempilo kanye nabalimi ekulweni nokutheleleka ngempumelelo.