Umkhiqizi wase-China u-Thiostrepton Ikhwalithi Ephezulu 99% CAS No 1393-48-2

Isingeniso

I-THIOSTREPTON iyimithi elwa namagciwane enamandla etholakala emikhiqizweni yokuvutshelwa kwezinhlobo ezithile zebhaktheriya i-Actinomycete. Ingokwesigaba se-thiopeptide yemithi elwa namagciwane futhi isiye yaqashelwa ngokusebenza kwayo okumangalisayo ezinhlobonhlobo eziningi zamagciwane e-Gram-positive, kuhlanganise ne-MRSA (i-Staphylococcus aureus engamelana ne-methicillin).Thiostreptonicutshungulwe kabanzi futhi ikhombise isithembiso ezinhlelweni ezahlukene zezokwelapha, zezilwane nezolimo. Ngezici zayo eziyingqayizivele nezici ezivelele ze-antimicrobial, i-Thiostrepton iyaqhubeka nokushintsha insimu yokwelapha ngama-antibiotic.

Ukusetshenziswa

Ukusetshenziswa okuyinhloko kwe-Thiostrepton kusekwelapheni nasekuvimbeleni izifo ezibangelwa amagciwane. Ivimbela ukwakheka kwamaprotheni kuma-bacteria, ngaleyo ndlela ivimbele ukukhula nokwanda kwawo. Lokhu kuyenza ibe ithuluzi eliyigugu ekulweni nezifo ezihlukahlukene ezibangelwa amagciwane e-Gram-positive, kusukela ezifweni zesikhumba kuya ezifweni zokuphefumula. Ukwengeza, i-Thiostrepton iphinde yafakazela ukuthi isebenza ngokumelene nezifo ezithile zesikhunta. Umsebenzi wayo we-spectrum obanzi uyivumela ukuthi iqondise izinhlobo eziningi zezifo ezibangelwa amagciwane, okuyenza ibe isibulala-magciwane esisebenza ngezindlela eziningi.

Isicelo

1. Ukunakekelwa Kwezempilo Kwabantu: I-Thiostrepton ibonise amandla amakhulu ezinhlelweni zokunakekelwa kwezempilo kwabantu. Ngokuvamile isetshenziselwa ukwelapha izifo zesikhumba ezifana ne-impetigo, i-dermatitis, ne-cellulitis ebangelwa i-Staphylococcus aureus ne-Streptococcus pyogenes. Ngaphezu kwalokho, i-Thiostrepton ibonise imiphumela ethembisayo ekwelapheni izifo zepheshana lokuphefumula, okuhlanganisa inyumoniya kanye ne-bronchitis. Umsebenzi wayo omelene ne-MRSA, uhlobo oludumile olumelana nama-antibiotic, uye wayenza ibaluleke kakhulu ezindaweni zasesibhedlela.

2. Imithi Yezilwane: I-Thiostrepton iphinde yathola ukusetshenziswa okubanzi emithini yezilwane. Ibhekana nezifo ezihlukahlukene zamagciwane ezithinta imfuyo, izinkukhu, nezilwane ezihambisana nazo. Ukusebenza kwayo ngokumelene namagciwane avamile afana ne-Staphylococcus, i-Streptococcus, nezinhlobo ze-Clostridium kube negalelo elikhulu ekuthuthukiseni impilo nempilo yezilwane. Ngaphezu kwalokho, iphrofayili yezokuphepha enhle kakhulu ye-Thiostrepton ikwenza kube ukukhetha okuhle kokwelapha izifo ezilwaneni, kuncishiswe imiphumela engemihle engaba khona.

3. Ezolimo: I-Thiostrepton inamandla amakhulu ekusetshenzisweni kwezolimo. Ingakwazi ukulwa namagciwane ezitshalo afana ne-Actinomyces kanye ne-Streptomyces, inciphise izehlakalo zezifo zezitshalo futhi ithuthukise isivuno. I-Thiostrepton ingasetshenziswa njengesifutho se-foliar noma ekwelapheni imbewu ukuze inikeze ukuvikeleka ekuthelelekeni kwefungal kanye namagciwane ezitshalweni ezihlukahlukene. Ngokulawula izifo zezitshalo ngokuphumelelayo, i-Thiostrepton ifaka isandla ekulimeni okusimeme kanye nokuvikeleka kokudla.

Izici

1. Amandla:Thiostreptonidume ngamandla ayo ahlukile ezinhlobonhlobo zamagciwane ayingozi kanye nesikhunta. Isebenza ngokuvimbela ngokukhetha ukuhlanganiswa kwamaprotheni e-bacterial, iqinisekisa isenzo esihlosiwe ngokumelene nama-microorganisms we-pathogenic ngenkathi igcina amagciwane anenzuzo.

2. I-Broad Spectrum: Umsebenzi we-Thiostrepton uhlanganisa amagciwane amaningi e-Gram-positive ngisho nezinhlobo ezithile ze-anaerobic. Lokhu kuguquguquka kuvumela uhla olubanzi lwezinhlelo zokusebenza ezilungiselelweni ezahlukene zezokwelapha, zezilwane nezolimo.

3. Ukuphepha: I-Thiostrepton ibonisa iphrofayili yokuphepha enhle kakhulu, iyenze ifanelekele ukusetshenziswa ezinhlotsheni ezihlukahlukene. Ubuthi bayo obuphansi kanye nemiphumela engemihle enganakwa kuvumela ukusetshenziswa kwayo ezindaweni ezibucayi, njengamayunithi e-ICU namapulazi ezilwane.

4. Ukuvimbela Ukumelana: Ngokungafani namanye ama-antibiotics, i-Thiostrepton ibonise ukuthambekela okuphansi kokuthuthukiswa kokumelana namagciwane ngenxa yendlela yayo eyingqayizivele yesenzo. Lokhu kuyenza ibe ithuluzi elibalulekile ekulweni nodaba olukhulayo lokumelana nama-antibiotic.

5. Ukuhlukahluka Kokwakhiwa: I-Thiostrepton itholakala ngezindlela ezihlukahlukene, kuhlanganise nokhilimu, amafutha okugcoba, imijovo, nezifutho. Lokhu kusiza ukuphatha kalula ezindaweni ezahlukene zokunakekelwa kwezempilo nezolimo, kusiza abahlinzeki bezempilo kanye nabalimi ekulweni nezifo ngempumelelo.