I-Doxycycline HCl CAS 24390-14-5 esezingeni eliphezulu ngentengo engcono kakhulu

Ngokubopha ngokuphindisela kwi-receptor ku-subunit engu-30S ye-ribosome yebhaktheriya, i-doxycyclin iphazamisa ukwakheka kwe-ribosome complex phakathi kwe-tRNA ne-mRNA, futhi ivimbela uchungechunge lwe-peptide ukuthi lukhulise ukwakheka kwamaprotheni, ukuze ukukhula nokuzalela kwamagciwane kuvinjelwe ngokushesha. I-Doxycycline ingavimbela amagciwane ane-gram-positive kanye ne-gram-negative, futhi inokumelana okuphambene ne-oxytetracycline kanye ne-aureomycin.

Aukuhlanganiswa

Ukwelashwa kwezifo ezithathelwanayo ezibangelwa amagciwane ane-gram-positive kanye ne-gram-negative kanye ne-mycoplasma, njenge-porcine mycoplasma, i-colibacillosis, i-salmonellosis, i-pasteurellosis, njll.

Ukusabela okubi
Ukusabela okubi okuvame kakhulu kwe-doxycycline hydrochloride yomlomo ezinjeni nasemakatini ukuhlanza, uhudo, kanye nokuncipha kwesifiso sokudla. Ukuze kuncishiswe ukusabela okubi, akukho ukwehla okukhulu kokumuncwa kwemithi okubonwe lapho kuthathwa nokudla. Ama-40% ezinja ezithole ukwelashwa abonise ukwanda kwama-enzyme ahlobene nokusebenza kwesibindi (i-alanine aminotransferase, i-alkaline phosphatase). Ukubaluleka komtholampilo kokwanda kwama-enzyme ahlobene nokusebenza kwesibindi akukacaci.