I-Azithromycin 98%TC

Incazelo Yomkhiqizo

I-Azithromyciniyi-Semisynthesis enamalungu ayishumi nanhlanu e-Macrolide antibiotic.I-crystalline powder emhlophe noma ecishe ibe mhlophe;Ayikho iphunga, ukunambitheka okubabayo;I-hygroscopic kancane.Lo mkhiqizo uncibilika kalula ku-methanol, i-acetone, i-chloroform, i-anhydrous ethanol noma i-dilute hydrochloric acid, kodwa cishe ayincibiliki emanzini.

Izinhlelo zokusebenza

1. I-acute pharyngitis kanye ne-Tonsillitis eyingozi ebangelwa i-Streptococcus pyogenes.

2. Ukuhlasela okunamandla kweSinusitis, i-Otitis media, i-Acute bronchitis kanye ne-bronchitis engapheli ebangelwa amagciwane azwelayo.

3. Inyumoniya ebangelwa i-Streptococcus pneumoniae, Haemophilus influenzae kanye ne-Mycoplasma pneumoniae.

4. I-Urethritis kanye neCervicitis ebangelwa i-chlamydia trachomatis kanye ne-non-multidrug resistant neisseria gonorrhoeae.

5. Izifo zesikhumba nezicubu ezithambile ezibangelwa amagciwane azwelayo.

Izinyathelo zokuzivikela

1. Ukudla kungathinta ukumuncwaI-Azithromycin, ngakho-ke idinga ukuthathwa ngomlomo ihora elingu-1 ngaphambi kokudla noma amahora angu-2 ngemva kokudla.

2. Ukulungiswa komthamo akudingekile ezigulini ezinokwehluleka kwe-renal okuncane (i-creatinine clearance>40ml/min), kodwa ayikho idatha ngokusetshenziswa kwe-azithromycin Erythromycin ezigulini ezinokwehluleka kakhulu kwezinso.Kufanele kuqashelwe lapho kunikezwa i-azithromycin Erythromycin kulezi ziguli.

3. Njengoba uhlelo lwe-hepatobiliary luyindlela eyinhlokoI-Azithromycini-excretion, kufanele isetshenziswe ngokuqapha ezigulini ezinokukhubazeka kwesibindi, futhi akufanele isetshenziswe ezigulini ezinezifo ezinzima zesibindi.Ukulandelela njalo ukusebenza kwesibindi ngesikhathi somuthi.

4. Uma ukungezwani komzimba kwenzeka ngesikhathi somuthi (njenge-angioneurotic edema, ukusabela kwesikhumba, i-Stevens Johnson syndrome, ne-epidermal necrosis enobuthi), umuthi kufanele umiswe ngokushesha futhi kuthathwe izinyathelo ezifanele.

5. Ngesikhathi sokwelashwa, uma isiguli sinezimpawu zohudo, i-pseudomembranous enteritis kufanele icatshangelwe.Uma ukuxilongwa kutholakala, izinyathelo ezifanele zokwelashwa kufanele zithathwe, okuhlanganisa ukugcina amanzi, ibhalansi ye-electrolyte, i-protein supplementation, njll.

6. Uma kukhona izehlakalo ezimbi kanye/noma ukusabela kwenzeka ngesikhathi kusetshenziswa lo mkhiqizo, sicela uthintane nodokotela.

7. Uma usebenzisa eminye imithi ngesikhathi esifanayo, sicela wazise udokotela.

8. Sicela uyibeke lapho izingane zingafinyeleleki khona.