Ikhwalithi ephezulu yeVeterinary Pharmaceutical Antibiotic Florfenicol CAS 73231-34-2
I-Flofenicol iyimithi elwa namagciwane evame ukusetshenziswa kakhulu ene-antibacterial spectrum, umphumela onamandla wokulwa namagciwane, i-low minimum inhibitory concentration (MIC), ukuphepha okuphezulu, ukungabi nobuthi, futhi akukho zinsalela. Ayinayo ingozi engaba khona yokubangela i-aplastic anemia futhi ifanele amapulazi amakhulu okuzalanisa. Isetshenziselwa ikakhulukazi ukwelapha izifo zokuphefumula zezinkomo ezibangelwa i-Pasteurella ne-Haemophilus bacteria. Inomphumela omuhle wokwelapha ekuboleni kwezinyawo zezinkomo okubangelwa yiClostridium. Ibuye isetshenziselwe izifo ezithathelwanayo ezibangelwa amagciwane azwelayo ezingulubeni nasezinkukhuni, kanye nezifo ezibangelwa amagciwane ezinhlanzi.
Inkomba
1. Imfuyo: ukuvimbela nokwelashwa kwesifuba somoya ezingulubeni, i-pleuropneumonia esithathelwanayo, i-atrophic rhinitis, isifo se-swine pulmonary, isifo se-streptococcal esibangelwa ubunzima bokuphefumula, ukukhuphuka kwezinga lokushisa, ukukhwehlela, ukuminyanisa, ukwehla kokudla, ukumosha, njll., kunomphumela onamandla. ku-E. coli nezinye izimbangela zengulube yengulube esiphuzi nesimhlophe sohudo, i-enteritis, isifo sohudo lwegazi, isifo sokuvuvuka nokunye.
2. Izinkukhu: ukuvimbela nokwelashwa kwenkukhu ebangelwa i-E. coli, i-Salmonella, i-Pasteurella nezinye ikholera, isifo sohudo esimhlophe, isifo sohudo, isifo sohudo esingalapheki, indle eluhlaza ephuzi, indle enamanzi, isifo sohudo, i-punctiform yamathumbu emathunjini noma ukuphuma kwegazi. i-omphalitis, i-pericardium, isibindi, amagciwane, i-mycoplasma yabangela izifo ezingapheli zokuphefumula, infectious rhinitis ibhaluni ibhaluni turbidity, ukukhwehlela, uqhoqhoqho, njll. dyspnea
3. Inomphumela osobala ku-serositis ethathelwanayo, i-Escherichia coli ne-Pseudomonas aeruginosa kumadada.
4.Okwemikhiqizo yasemanzini.Ukwelashwa kwezifo zezinhlanzi ezibangelwa amagciwane, ezithathwe ngaphakathi.
Umthamo :10-15mg/kg(okuhlobene nesisindo senhlanzi), kabili ngosuku (lesi sidakamizwa siyashukumisa, sihlukaniswe izikhathi ezimbili), ngokuvamile izinsuku ezintathu zokwelashwa. Ama-shrimp kanye nezinkalankala zinamathumbu amafushane. Phinda kabili umthamo.Qaphela: Sebenzisa ngezinsuku libalele.
I-Flufenicol iyahambisana
1. Kuhlanganiswe neomycin, doxycycline hydrochloride, colistin sulfate, loricin, njll, umphumela wokwelapha uyathuthukiswa.
2. Kuhlanganiswe ne-ampicillin, i-cefradine, i-cephalexin, njll, ukusebenza kahle kuyancipha.
3. Ukuhambisana ne-kanamycin, i-streptomycin, i-sulfonamides ne-quinolones kwandisa ubuthi.
4. Ihambisana ne-VB12, ingavimbela i-erythropoiesis.
Isenzo se-Pharmacological
Ingasakazwa kumaseli ebhaktheriya ngokuncibilika kwamafutha, ikakhulukazi esebenza ku-50s subunit ye-70s ribosome yamagciwane, ivimbele i-transpeptidase, ivimbele ukukhula kwe-peptidase, ivimbele ukwakheka kweketango le-peptide, futhi ngaleyo ndlela ivimbele ukuhlanganiswa kwamaprotheni ukuze kuzuzwe. izinhloso zokulwa namagciwane. Lo mkhiqizo une-spectrum ebanzi ye-antibacterial futhi unemiphumela enamandla kubhaktheriya e-Gram-positive ne-Gram-negative kanye ne-mycoplasma. Lo mkhiqizo unokumuncwa ngomlomo ngokushesha, ukusatshalaliswa okubanzi, uhhafu wempilo ende, ukugcwala kwezidakamizwa egazini kanye nesikhathi eside sokugcinwa kwezidakamizwa egazini.